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Philip Farrant | | Consultant in General MedicineBorn in Bristol in 1925.
Overview: Dr. Philip Farrant was a general physician at West Hill Hospital in Dartford from 1963 to 1988. He was never officially designated as having a ‘special interest in diabetes`, but he ran the diabetic clinics and published on diabetes. In 1976, he encouraged a patient to found a local branch of the British Diabetic Association, which raised money for equipment and offered support to patients. In 1972, he established a postgraduate medical centre at Joyce Green Hospital, which moved to the new Darent Valley Hospital in 2000 and was re-named the Philip Farrant Education Centre. | [View Full Interview] |
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67
| (1) Tell me about your background.
I was born in
Bristol in 1925, and went to school locally, and then I
went to a public school in
Dorset in
1938. And I did classics at school, and
clearly, I wasn‘t nearly as good a classicist as I thought I was. And so, I had always wanted to do - well,
latterly - I had always wanted to do medicine, and so I changed courses, in
mid-stream, if you like, towards the end of my school career. And I was able to get in - on School Cert, it
was called, in those days - I was able to get in as a medical student in
Bristol, and I went to
Bristol in 1943. And I was in a reserved occupation, being a
medical student, and I think I‘ve had guilt feelings about that ever since. I‘m told that‘s ridiculous, and, of course, I
did do national service in the army later on, but I still have guilt feelings,
which are not tremendously active now, but I think I still have them. And I ought to have done my bit, and either
survived or not. So, anyway, here we
are, then. I go to
Bristol in 1943. And anyway, if one was worried about the
army, one was partly in the army, in
Bristol,
because we had a senior training corps, which was quite tough training. I mean, every Sunday and one afternoon we
would do drill, and all that sort of thing. Anyway, forget that. I‘m now into
anatomy... no, I‘m not; I‘m sorry. In
1943, I still have to do some biology, some physics - which I very much enjoyed
- and so on, so that actually, it‘s 1944 when I begin my so-called pre-clinical
studies in
Bristol. And that‘s two years of anatomy, physiology…
well, mainly that. And then, two years
later, I actually become a clinical medical student; so, that will be in 1946,
when the war is over.
| (2) Can you remember your first encounters with people
with diabetes?
I really can‘t,
no. I mean, when you‘re a medical
student, you are aware of what‘s going on, and you are, in a way - in a very
small way - a member of a team. So that,
I mean, one did see patients admitted with diabetic ketosis, and how they were
treated, but I had no exposure to a diabetic clinic. I‘m not even sure whether… I don‘t know that there
was one, in those days. So, no; no
special exposure to any particular disease, because we were just trained
as... They always told us we would be
general practitioners, and somehow, or other, I decided that I didn‘t actually
necessarily want to be labelled as a future general practitioner. I jolly nearly was, as may come out
later. So, that‘s how we were trained:
to tackle most things, and, of course, that can no longer apply. We‘ve got four medical student grandchildren,
and I follow their careers with interest, and realise how very different they
are from my own.
What are the
main differences between your training and your grandchildren‘s training?
Well, one of the
main differences is they don‘t do - and that‘s quite right, unless you want to
be a surgeon - they don‘t do all that much anatomy. I mean, they do enough, but we took a whole
term over the anatomy of the arm, and another whole term over the anatomy of
the leg, including the pelvis, et cetera, et cetera. They are much earlier, now, exposed to
scientific medicine; I mean, immunology, and all that that goes with. And also, of course, they‘re exposed to
patients much earlier than we were. They
go - in the first year - they go and interview patients, and get to grips with
taking a history from patients, which is, of course, what medicine is really
all about. It‘s taking an adequate
history, and it isn‘t always done. But, in
that sense, they, you know, are... it‘s more like being a doctor from the word "go". And, of course, there are so many of
them. There were thirty people, in our
year - about half male, half female - and that was all. Well now, I mean, we‘ve got one of our
medical students is in
Bristol,
and they have something like two hundred and eighty. And the same can be said in
Birmingham, where we‘ve also got two medical
students. They‘ve got about three
hundred, I think, in a year. How they
cope with that, I don‘t know, but they do seem to be able to cope with it,
because it works extremely well.
|
| | (3) Can you remember what you were taught about
diabetes, during your training?
Well, yes. Of course, in physiology, we knew all about
insulin, we knew quite a lot about carbohydrate metabolism, and, thereby, we
were told what happened when there was a deficiency of insulin, and so
forth. In those days, I don‘t think the
distinction was made between what is now called Type 1 and Type 2 diabetes. So, I would have seen, as a clerk - we called
them clerks on the medical side, dressers on the surgical side - I would have
seen patients with diabetes, and, as I say, the occasional one with
ketoacidosis coming in, when one was on call with the rest of the firm. But certainly not much exposure to the
ravages of diabetes - that is to say the complications, which will come out
later. Not much of that, I think,
because, of course, they were more or less untreatable, in those days,
anyway. So, no, we got... I mean, we did six months, in all, as medical
clerks on medical firms. I was on a firm…
well, I was later on the medical professorial firm. And one just saw what came in the front door,
which is, in those days, what general medicine was all about.
What did you do
when you completed your training?
Well, there were
clearly two six month house jobs to be done. I think you only had to do one, but I thought I would do two. And that meant deferring National Service in
the army or air force or navy, which was a formality. So, my first house job was as a house surgeon
to Professor Milnes Walker, who was professor of surgery. And he‘d been a very effective, and
well-known - and loved, I think - surgeon in
Wolverhampton,
and, as such, did everything, again, that came in through the front door. He could do neurosurgery or he could do
orthopaedic surgery. But when he became
professor of surgery in
Bristol,
he had a more limited type of case that he was dealing with. So, I was his house surgeon, and very
valuable experience I found that to be. Then I went to a medical firm, where I was a house physician. And, again, we treated emergencies of all
sorts. And I do remember one patient
coming in with Addisonian Crisis. That‘s
not really anything to do with diabetes, but I‘m sure that we would have
treated one or two other cases of diabetic ketoacidosis, which was always
rather a fraught situation, and had quite a high mortality, in those days.
|
| | (4) What did you do after you‘d completed your
two house jobs?
Well, I went up
to
Sheffield - I went there again later - for
about a year, as a very junior pathologist, which was a good training for
general medicine. And so, I did that for
a year, which was quite... which was rewarding. And then I went into the army, and in the army, I was, of course, a
junior pathologist. And after the
initial sort of square-bashing, and so on and so forth, down in Hampshire, I
went to Singapore and Malaya, where I was what was called a junior graded
pathologist, so I was working in a lab. And one was exposed, there - and in Malaya itself - to a lot of tropical
medicine, which I found quite interesting, but, of course, not diabetes at all,
because anybody who had diabetes would either not get into the army, or if they
were discovered to have diabetes in the army, would be promptly repatriated
home. So, of course, that was one
condition that I did not see at all, at that time, but there was plenty of
other things. So, having spent some time
up-country in Malaya, where one thing I had to do was to try and investigate an
outbreak of amoebic dysentery in a Scottish Battalion, in the middle of a
jungle, which… that was quite interesting, and they were very, very nice to
me. Then, I got back to
Singapore
,
and I had, by this time, I had acquired a wife and a child. So, my wife - we had no special local
overseas allowance, as one would have done had one been in a short-service
commission - so my wife had to work teaching French and English, and perhaps a
bit of Latin, in a convent in Singapore, so we were able to keep going. Anyway, I got myself back, in
Singapore
, to the lab at the
Queen
Alexandra
Hospital. And there, one day, I got a phone call from
the Department of Pathology at the university in Malaya, which was then in
Singapore
:
would I go and help out teaching dental students pathology? So, that was rather fun, so I did that. And it did, actually, help me apply for a job
when I left the army.
|
| | (5) What did you do after you left the army?
So, I got
demobbed, and it was around 1953, and I went to work in the Department of Pathology
in
Bristol. And, of course, having had a minuscule
academic responsibility in
Singapore
,
it probably helped me get the job. I did
too much pathology: it went on from 1953 to ‘55. And it‘s an excellent training for being a
physician, but also, you have to get up a few rungs on the ladder, and so it
was a separate ladder that I was climbing. And so, I had to do something about it, and the first thing to do was to
get the MRCP exam - the membership exam - which I had considerable trouble with,
taking it several times before I eventually got it. And I then, while that was going on, became a
senior house officer on the medical professorial unit. And there, again, one would have seen people
with diabetes, and, by this time, the complications thereof. But I had no responsibility for a diabetic
clinic, as such. By 1956 to ‘58, I got a
research post, which enabled me to complete an MD, which was on a
haematological subject, and nothing whatever to do with diabetes. But, anyway, I got that. And this, and the membership, enabled me to
apply for a senior registrar appointment, which, in those days, was split; the
idea being that you went to a peripheral hospital to start with, and came up
against the usual sort of problems, and then you went to a teaching hospital,
which in my case was Sheffield, and you there were able to do a bit of
research, which I found... I found it quite difficult. A very nice boss; I worked with a very nice
boss, who said "Philip, on Wednesday afternoons, you‘re free to go and
think". Well, if someone tells you
to go and think, in my case, it has a negative effect. And I did, eventually, get going on
something, which was actually related to diabetes. It didn‘t work out terribly well. The first thing I did was to team up with the
Department of Physics in
Sheffield, to try and
look at insulin antibodies, which were just beginning to be talked about. And the way of doing that was to label
insulin with radioiodine, and then do electrophoresis measurements on the serum
of patients who looked as if they might have insulin antibodies. The trouble was, of course, the technique
hadn‘t properly been worked out, so it all came to nothing, because the
radioiodine, which was quite... had a high activity, in fact denatured some of
the insulin. So, reluctantly, we had to
abandon that. And I did work with a
bacteriologist looking at deposits of insulin binding, I suppose they were, in
diabetic kidney. That, actually, did
produce a paper, which I read to the British Diabetic Association in
Cardiff, a year or two
later. So, anyway, while I was a senior
registrar, of course, I did do, in
Sheffield,
a diabetic clinic with my boss. That was
one morning a week, so one was soon into all the things that people, who are
interested in diabetes, talk about. And
so, I got quite useful experience there.
|
| | (6) So, in this diabetic clinic, after... in
about 1962, for the first time, the Department of Chemical Pathology was able
to do blood sugars, and we would be able to get the result while the clinic was
going on. So, of course, it did mean
that the patient would have to wait about thirty to forty minutes, while the
blood was processed. But that helped,
quite a bit, to know what the situation was with regard to control. Previously, of course, they did their own
urine sugars - as will come out again later, I think - and they had blood taken,
but you got the result of the blood the next day. Well, if it was very low, well too bad;
someone - they would have presumably had hypoglycaemia - and somebody would
have given them some oral glucose. If
they were very high, then one would take some action. If it was extremely high, one would try and
get them back. But, arising out of this
immediate blood sugar - the availability of blood sugars - we had a local MP -
I can‘t remember his name, and I certainly wouldn‘t give it - who was an
established insulin-requiring diabetic. My boss was away, and this particular MP said to the house governor
"when I go to the diabetic clinic, I want it to be exactly the same as
everybody else". Very laudable
sentiments. So, he was treated exactly
the same as everybody else, which, of course, in his case, meant waiting thirty
to forty minutes to get the results of the blood sugar, during which time, he‘d
rung up the house governor and said how he‘d had to wait an unduly long
time. So, the house governor rang me,
and I talked to the patient, and all was calm again. But he had the right motives in his
mind. So, with regard to complications:
of course, all we could really do - retinopathy, no special treatment - all we
could really do was reinforce the idea that patients on insulin, or even not,
should try and control their diabetes as carefully as they could. I don‘t know that we particularly mentioned
the idea that they should stop smoking. I really can‘t remember what we said about smoking. It was clearly very important in the
development of peripheral vascular disease. I guess we did say "you mustn‘t smoke", but I don‘t imagine we
stressed it as much as we perhaps should have done. So, with regard to the other complications,
the peripheral neuropathy, which diabetics get, we could only say, well, one
would have to manage one‘s diabetes as carefully as possible. And the same really went for the neurology. Sorry, I‘ve already said that; I beg your
pardon.
|
| | (7) Can you give me a picture of your diabetes
clinic in these years, 1960 to ‘63?
Yes, my boss
would see the new patients, and they would return a week later, with a
diagnosis made and blood sugars, and so forth. And I would see them from then on, and I would see the majority of the
follow-up patients who were part of the clinic. I couldn‘t give you an idea exactly how many, but we would see, in the
course of a morning, I suppose, about thirty patients, follow-up patients. If patients needed to be admitted, which was
usually because they had to go onto insulin, there was no way in which we could
treat them in their homes, as now happens. So, they would be admitted into one of our two wards. And the ward sisters would - and the
dietitian - would manage their diabetes, and try and indoctrinate them with the
diabetic life. We did, in fact - I
shouldn‘t say this- but my boss was a very literary man. And we used to stop for coffee, in the middle
of the clinic, and we would discuss all sorts of fascinating things about
English literature, and also about painting and so forth, which I very much
enjoyed. But I was also slightly guilty,
that, you know, they saw two cups of coffee going into the consultant‘s
room. And so I resolved, when I ever got
a job, that, even if I did drink coffee in the morning, I would quite obviously
not stop the clinic. And that might come
out later, I don‘t know.
And can you tell
me about the staff of the clinic?
Well, I don‘t
think we would have used the word ‘team‘, in those days. I mean, there was the consultant in charge,
and there was me - the senior registrar - and there was also a registrar who
alternated with me on some of the clinics. There was a dietitian. There
wasn‘t - certainly the term podiatry had not been invented - I don‘t think
there was a chiropodist, but we could get - when they were admitted to hospital,
if necessary - we could get chiropody done. So, that was a team, as far as I can recall. It wasn‘t very extensive.
What about
nursing?
Ah, well, the
nursing: we would have, of course, the outpatient sister, who would be busy
doing all sorts of things. And again,
patients would be admitted, if they needed insulin, where they would be exposed
to the very good advice from the two ward sisters; male and female. I can‘t recall how much a nurse would have
contributed to their diabetic management, in the clinic; I really can‘t
remember that.
|
| | (8) Have you any other memories of this period,
‘60 to ‘63?
Yes, with
another senior registrar at the Sheffield Infirmary, we both - he dealt with
diabetes in the Infirmary, we dealt with it in the
Royal
Hospital - we both got a bit
interested in the management of diabetic pregnancy, which was then at the
Jessop
Hospital
for Women. And we tried to inculcate the
idea of good control, as far as possible, with these ladies. And we didn‘t, sort of, write a paper, or
anything. We just, sort of, tried to do
our best, and co-operated a bit on views of how we should proceed, and so
forth. I hope it helped, but, again,
there was no evaluation of that, because he moved away, and then I moved
away. I‘m sure, then, we would have
stressed the importance of not smoking, clearly; although, I don‘t recall that
as being a specific item on our agenda.
And what were
the outcomes for women with diabetes, in the early sixties?
The outcomes
were, well, not good. I mean, still births
- I can‘t give a figure - but still births were alarmingly common. We, of course, began… I mean, Peel and Oakley,
in King‘s
College
Hospital, had published
papers already, showing that the problem, of course, is the size of the
baby. We knew all about that, and we
knew all about trying to ensure that delivery, whatever method was used - usually
by Caesarean section - was done at, say, thirty seven weeks. And they had shown, in King’s
College
Hospital, that this altered the...
reduced, markedly, the still birth rate. I can‘t give the figures; they‘re in the literature. So, of course, we would have done that. We did not have a combined clinic with
obstetricians, which I‘m sure we ought to have done. But, I suppose, our interest in diabetic
pregnancy only spanned about a year, at the most, because he moved away, as I
said, and so did I.
|
| | (9) So, before we move on to
Dartford,
where you spent most of your career, any more memories?
Yes, I do
remember, when I was in
Bristol,
in the spring-summer of 1956, one‘s duties as an SHO were to help with the medical
Finals. And, to that end, one consulted
the ‘black book‘, which consisted of a number of patients who would be willing
to come up for examination. And one
particular case, I do remember - and I knew this man quite well. He was a diabetic, he had severe retinopathy
- and I said… And that was quite
legitimate, I think, for a medical student to be able to look at the fundus,
through an ophthalmoscope, and have a good shot at seeing what was then florid
and sight-threatening retinopathy. So, I
got this man in, and I said "look, the examiners want to go round looking
at the cases at
nine o‘clock
in the morning, so please, please, would you not be late?" So, he said no, he wouldn‘t be late, and he
wasn‘t late. But because he hurried so
much, he missed his breakfast. So, the
next thing I knew was Professor Perry, who was professor of medicine, shouted
from one end of the ward, he shouted "Farrant! This man‘s unconscious. Come and do something!" So, I realised that this man had become
hypoglycaemic. So, I stopped what I was
doing, and injected him with glucose, and he was fine, and then the medical Finals
went on. And I hoped they looked at his
retinae; I‘ve no idea whether they did or not. And the other thing, that‘s just occurred to me, is that when I was in
Derby, which would have
been between 1956 and ‘58 (in fact
1958-60), Bryan Matthews - who was a general physician with an interest in
neurology, and a very clever, nice physician. I worked for him. He later became
professor of neurology at
Oxford
- and he was doing estimations of nerve conduction time in all sorts of
conditions, not least in patients with diabetic neuropathy. And I assimilated this technique - he let me
use his apparatus - which is a standard technique, in those days, and may still
be in neurology. And the idea I had was
to try and estimate nerve transmission velocity in the leg, in patients who
were admitted in diabetic ketosis, because I reckoned there must be some delay,
which might have a bearing on whether or not, later on, they got
neuropathy. But, like so many of my
research ideas, that was a nice idea, and Dr Matthews went along with this, but,
in fact, there was so much disturbance going on when you treat someone with
diabetic ketoacidosis, that we were quite unable to get any recordings
whatsoever. So, that was another piece
of research which went down the drain. Sorry, I must just correct the dates. When I was in
Derby,
it was between 1958 and 1960, and not what I said before, which was earlier.
|
| | (10) And now tell me about moving to
Dartford.
Well, that was
in the Autumn of 1963, and we were all, then, appointed as general physicians,
without a special interest being designated. And on my first day, which was a Monday, I met George Stratton, who was
extremely helpful throughout my career - he‘s now dead, unfortunately - who, on
that Monday morning, greeted me when I went to
West
Hill
Hospital. And he said "Philip" - I think he
probably did use my Christian name - he said "Philip, on Thursday, there‘s
a diabetic clinic. I wonder if you could
possibly do that". I said
"yes, of course I could". And
from that moment on, I became interested in - officially - in diabetes and
endocrinology, and so forth. So, that‘s
how it happened with me, and maybe with other people as well.
Would your title
have included "with a special interest in diabetes"?
No, there would
have been... there was no special title. I mean, I just sort of did the clinic. And throughout my time in Dartford, I think - although I established a
thyroid clinic later, and so on and so forth - I was not sort of known, in
print, as an endocrinologist. I mean,
the surrounding general practitioners would know what my special interests
were, such as diabetes and thyroid disease, and so on, but there was no official
designation. When I got to
Dartford, the dietary control of diabetes was done with a
dietitian, who was very efficient. I
think she was occasionally… she occasionally put patients off, by insisting too
much on absolute adherence to her advice. I may be doing her wrong. I‘m
afraid I don‘t think she‘s alive now, so she can‘t answer the question. But sh e was invaluable. I mean, that
was perhaps her only fault, was she was slightly too militaristic, at times.
|
| | (11) Most of the patients - and the clinic was not
very large: what, I suppose, a total of a hundred or a hundred and fifty, or
something - they would be seen at perhaps three-monthly intervals. Most of the patients, of course, were on
diet, or diet and tablets. The diet
would be the old Lawrence Line diet, with ten gram portions of carbohydrate,
which the dietitian would explain to them. If diet didn‘t work - and they were, of course, measuring their urine
sugar. Not by the methods that are
available now, but with something called Clinitest, which involved test-tubes,
and the urine would be heated, and so forth, by the Clinitest tablet. Not all that easy, as compared with what it
is now. But, if they seemed to be
exhibiting poor control, as judged by the urine sugars, then we would go to a
sulfonylurea, such as, in those days, Tolbutamide. And that, we hoped, would redress the
situation, which it commonly did. And,
of course, one would also ask about diet; try to tighten that up a bit. Then, if Tolbutamide didn‘t work, then there
was something called Fenformin, which didn‘t work in the same way as the
sulfonylureas, but that was, after a few years, found to be slightly hazardous
on occasions, and was replaced by Metformin. Then other sulfonylureas came along, notably Chlorpropamide, which was
traded under the name of Diabinese. So,
most of our patients would then be on that. But those patients who arrived in the clinic with a new - particularly
if they were young - with a new diagnosis of diabetes, would be admitted to my
male or female ward, where the dietitian would follow them up. And the ward sisters, who were absolutely the
linchpin of insulin management, would explain to them what insulin was, how it
worked, how you injected it into an orange to start with, and all that. And then supervise their injections into themselves,
and their urine testing, supported, of course, by blood sugar measurements; the
result, of which, would come the following day. So, it was, by modern standards, I suppose it was primitive. We thought we were doing well; we were doing
as well as we could, I suppose, in the present state of knowledge. And that‘s how the clinic was. I was very ably helped by a succession of GP
- mainly GP - clinical assistants, who came in on the day in question, Thursday
mornings. Actually, when I first went there,
the clinic was in a very, very old building, which has now disappeared. And this building... the clinic was upstairs,
and I had said - without really thinking it out, I suppose - I had said that I
wanted the patients to be weighed each time they came. And there was one very efficient - very
accurate, I should say - very accurate weighing machine, weighing, you know, a
hundredweight and a half, I should think. And this was downstairs, in the waiting room, as such. And so, on that first clinic that I did, on
that Thursday - I didn‘t know it at the time - but a rather fat lady was asked
by the nurses if she would be weighed. And this, of course, was in front of everybody else. So, she made an official complaint against
the clinic, and me, who hadn‘t even seen her, at that time. This caused considerable amusement among my
colleagues, that this new physician from
Sheffield
and
Bristol had
had a complaint raised against him on the very first day that he did a clinic,
or a diabetic clinic. Well, the usual
administrative rigmarole was gone through, and, of course, everything was
settled. And I think, in a way, it might
have helped, because I think a new, rather lighter-weight weighing machine was
produced quite quickly, which enabled them to be weighed in privacy on the
clinic. But that was one of my first
introductions to the life of a physician in
Dartford.
|
| | (12) I ought to say a bit more about the clinical
assistants. I would be quite unable to
have run the clinic at all, without them. I say "them"; there was only one, at any one material
time. One of them - Mrs Corley - was
extremely interested in diabetes, and was very helpful, as they all were. But then, when she‘d been with me for, I
should think, a couple of years, Dr David Pike - who is now dead unfortunately,
and was the diabetic expert at King‘s College Hospital - rang me up. And he said "we want an extra clinical
assistant for our diabetic clinic. You
have Mrs Cawley", you know, "what do you think?" So, I said "well, if you possibly can,
get her", which, of course, was not very good for me, because she actually
left. And other very good people came
along afterwards. She now lives in
Gloucestershire, and she doesn‘t have anything to do with diabetes, as far as I
know, but we have Christmas cards every Christmas.
You mentioned
those who were admitted to a ward. Do
you know how long they were admitted for?
I suppose they
would be admitted - they had to learn the whole gamut of diabetic advice, you
see - I suppose certainly ten days to a fortnight. Sometimes it would be three weeks, while the
dietitian and the ward sister would make sure that they knew how to make the
jump from being in hospital, where we had facilities for blood sugar
measurement, and there were doctors on hand, and so forth. I now realise - or maybe I realised a bit
later in my career - what a huge jolt it must have been for anybody to suddenly
realise that they‘d been thirsty for say a few weeks, or a few days, sometimes,
and suddenly they had a disease which they knew nothing whatever about. And they have to make the jump and think
about their future career as housewives, or as workers of various sorts. And that‘s where the ward sisters, I‘m sure,
would have been able to help them much more than I ever would be, because they
sort of knew what these people were exposed to. So, I expect it sometimes would have taken three weeks, and, on
occasions, of course, longer. Throughout
my career, I began to realise what the effect of the diagnosis of diabetes
would have on people. I was a bit slow,
I think, in realising this. Maybe we all
were; but that will come out a little bit later in my talk, I think.
|
| | (13) Did you have any educational literature to
give to patients?
Yes. When I got to
Dartford,
there was a booklet describing diabetes, and I, of course, read it. And I was quite appalled by one sentence in
it, which was to do with genetics, I suppose. And it said "two diabetics should never marry". I was absolutely appalled by this, and I got
them to pulp all these booklets immediately, on about the second time I did a
clinic. And then I wrote another one,
with the aid, I think, of the British Diabetic Association. And I think, in fact, initially - before I
wrote this - I think we used the literature which the BDA - the British
Diabetic Association - produced, which was extremely helpful for them all. So, they all got this literature, and they
could, of course, join the BDA and get further advice, in this way. The insulin-requiring diabetic patients, of
course, were... they were provided with
syringes, which were glass syringes, which were kept in spirit-filled
containers, and they would be sterilised at home. And, of course, they were shown how to do it
in the ward by boiling. And, of course,
there were some cases of sepsis at the injection site, which is inevitable when
the... perhaps they didn‘t boil the syringes all that often, and in the dash
and hurly-burly of life, they didn‘t actually always carry out what we said,
and I can‘t blame them for one moment. But there were some instances of sepsis. Nowadays, of course, the delivery of insulin has been changed out of all
recognition, by the development of the insulin pen, and by disposable syringes,
and properly sharpened needles, thin needles, and even by other ways of
administering insulin, by continuous insulin infusion. All of these were way beyond the horizon when
we started.
We‘ve talked
about education and insulin and diet and tablets. Was there any emphasis on exercise?
I don‘t think we
particularly suggested that regular exercise should be taken. In fact, I‘m sure we did not. And clearly we ought to have done, but that didn‘t
come in. I‘m not sure that I mentioned
chiropody, by the way. In the clinic,
there was a chiropodist - or rather, she wasn‘t actually in the clinic, but we
could refer patients to her. But it
really was, I imagine, would be described as fairly primitive chiropody, and
there was no... podiatry, as I mentioned before, was a word we hadn‘t even
heard of.
|
| | (14) Any more memories from the 1960s?
Yes, well, there
are. One particular item: the firm of
Burroughs Wellcome had been in
Dartford, I
should think, eighty years, by this time, and they were one of the main - they
and Boots - were the main manufacturers of bovine insulin, in those days. And the assay of insulin was governed by a
procedure from the... outlined by the British Pharmacopoeia, which involved the
use of animals, mainly mice. And, you
know, there was no method - until the very early sixties, when it came out in
America
, and
was taken up by the people at the
Royal
Free
Hospital
- there was no method for estimating insulin - human insulin - in blood; or
even bovine insulin, for that matter. But Burroughs Wellcome had an interest in this, because, of course, if you
could assay insulin by a quicker method, not using animals, it would be
obviously advisable. So, I got on to
this by about the mid-1960s; shall we say 1966. And I realised that they‘d got... they had a viable insulin assay going. And I was, at that time, interested, of
course, in diabetes, but also in obesity. And there were reports of high insulin levels in normal, non-diabetic
obese people. So, we did, in fact, do a
little bit of research, by measuring the response of insulin - that‘s to say
human insulin, produced by the patient himself or herself - after a, what was
called, an "oral glucose load". That‘s to say, the patients drank fifty grams of glucose in water, and
before they did this, they had a fasting insulin - and, of course, blood sugar -
taken. And then the research was to see
what happened to insulin levels in normal people - which we established a
baseline for - and in obese patients, before they‘d been put on a
weight-reduction regime. And there were,
in fact, very high insulin levels in such patients, after an oral glucose
load. And the same patients were then
examined - I think there were about eight in the experimental group - and we
showed that, after weight reduction, the level of insulin after a glucose load
was less - significantly less - than before treatment had started. We could not say, however, whether this was
due to the effect of weight reduction itself, or due to the diet itself, or
both. I read this paper, which I
published with George Stewart at the Wellcome Foundation, at - I think in 1969
- I read the paper at a meeting, at King‘s
College
Hospital,
of the medical section of the British Diabetic Association. And it was also published, that year, in
Diabetologia, which was the European Journal of Diabetes.
|
| | (15) Also, in the sixties, there was the idea,
abroad, that there should be postgraduate medical education. Under the terms of the medical act, which
brought in the Health Service in 1948, no money could be spent on anything
other than patient care. But by the very
early sixties, there was a conference at
Christ
Church,
Oxford - I
reckon it was in 1960 - when the importance of continuing education in medicine
was stressed. And, as a result of that,
a small amount of exchequer money was released to hospitals, which were
interested in this sort of thing, to establish some form of postgraduate
medical education. And I was fortunate
to get in on that fairly early. And the
university - whichever it was, wherever you were - the local university, in our
case London, established clinical tutors in various hospitals, whose job it was
to put on programmes of general interest to doctors - not just medicine:
surgery, obstetrics, ophthalmology, anything - so that people could have some
form of continuing education. We were
granted an honorarium of - by the time I became a clinical tutor, it was 1964 -
we had an honorarium of two hundred pounds in a year, which doesn‘t seem very
much now, but we were glad to get it. But we were much more glad to do something about continuing education;
for ourselves, if not for the rest of them. So, as a result of this, we established a small classroom in a disused
building, where we held various lectures, and so forth. And general practitioners could come, and
junior staff who were taking the membership, and junior surgical staff who were
taking the fellowship, and all that sort of thing, all started in the
mid-sixties. And it culminated, really -
well, culminated is the wrong word - but it resulted in the opening, in 1972,
of our postgraduate centre at
Joyce
Green
Hospital,
which was our main hospital.
Joyce
Green
Hospital had been built, originally,
as a smallpox hospital, in the days when smallpox in
London was rife, and patients would be
brought down by river to what were then called the river hospitals. And this - a huge building, series of
buildings - they were all exactly the same. All these ward blocks replicated each other; they were exactly the
same. And we had too many - they were
unused - so it wasn‘t difficult to persuade the authorities to adapt one of
these wards - ward 12A - to be the postgraduate centre. And this, of course, meant money. So, the Health Service provided some money,
the Wellcome Foundation provided some money, the King Edward VII Hospital Fund
for
London
provided some money, local GPs, local notables, and some… a few wealthy people
contributed money. We had to have a
fund-raiser, because doctors are hopeless at trying to get money out of
people. So, anyway, we got together
thirty two thousand pounds, which, again, doesn‘t seem a great deal these days. We had a building, of course; it just had to
be adapted. We had a very good
architect, and we had the state of the art, of the time, projection facilities,
and so forth. And so, it was opened in
1972, by Lord Rosenheim, who had been, until recently, the president of the
Royal College of Physicians. And it was
attended by, among other people, the Bishop of Rochester, who is - David Say -
who is also now dead, who had helped with our fund-raising appeal. And other people had also helped with
that. So, it was quite fun to do this,
but it was fairly time-consuming. And
the centre went on until the year 2000; it went on from 1972 to 2000, when the
hospital was moved to a new hospital, called the
Darent
Valley
Hospital, and, of course,
I had, by this time, long since retired.
|
| | (16) Well, while we‘re on the
Darent
Valley
Hospital: just before it
was commissioned, they had named all the wards after trees. There was Rowan Ward and Juniper Ward and Oak
Ward, et cetera, and Chestnut Ward, and all that. And they appeared to have run out of trees,
so somebody said, would I mind if my name, Philip Farrant, was given to the new
education centre. So, I said no, I
didn‘t mind at all, so long as they spelt Philip with one ‘l‘, which commonly
people don‘t. So, it is now - if you go
to the
Darent
Valley
Hospital,
you‘ll see a sign - Philip Farrant Education Centre. So, somebody said, at the time, they said
"well, you‘ll get immortality without actually dying", so I suppose I
have, until they think of some other name, which they probably will.
Before we move
on to the 1970s, any more memories from the 1960s?
Well, I think
that dialysis - renal dialysis - was beginning to be available for renal
failure; initially, of course, in non-diabetic patients, because it was
considered that perhaps diabetes had a bad prognosis, and the limited
availability of dialysis should be for patients who did not have another
condition; they only had their renal failure. But certainly by, I think, the later sixties, I had one patient - a
young girl of about twenty five, who had quite bad renal failure - and I was in
touch with St Mary‘s, Paddington, who were about the only people who were doing
this, at that time. And I have to say -
it‘s really rather irrelevant, I suppose - she was a dyed blonde. Very pleasant girl, she had quite bad renal
failure, and it was arranged that she should go for dialysis, or at least to be
considered for dialysis, at St Mary‘s, Paddington. So, she said on the ward round, she said
"could I go home, for one day? I
want to dye me roots". And her
roots, actually - you know, she‘s been in hospital with us, I suppose, for
about a month and a half, I should think; low protein diet, and all that - and
her roots were beginning to revert to their normal sort of brown colour. So, she went home and dyed her roots, and
went off to St Mary‘s, Paddington. But
I‘m afraid I... she did have dialysis,
but, of course, they followed her up after that, so I have no more information
on her. The various other complications,
we‘ll probably deal with a little bit later, in the seventies.
|
| | (17) So, in the seventies, the clinics began to
get much bigger. And this was a problem,
which I didn‘t tackle immediately. But
we did have, by this time, a new outpatient centre - a very good one - at West
Hill Hospital, which had been originally designated as the site of the new
hospital, which we all were... we were always told would be coming. In fact, it never did, because, one reason being,
there was no car parking available in the centre of
Dartford. Anyway, we had this new outpatient centre,
and still the diabetic clinic continued on a Thursday, but by this time, of
course, the clinic had got much, much larger, and this was beginning to be a
problem. We had established, with Queen
Mary‘s Hospital, Sidcup, a community liaison sister, who was specially trained,
or adopted special training in diabetes, so she would deal with all the new
insulin-requiring diabetic patients. And
she would show them how to do injections, and how to, by this time, estimate
their own blood glucose by the finger-prick method, because Dextrostix was
becoming available, by this time, but had to be bought - it wasn‘t available to
the patients themselves. But the result
of all this was that we did not always have to admit patients, who needed
insulin, to inpatient ward treatment. And this helped them quite a lot. It didn‘t do much to reduce the number of patients, of course. But one thing that did begin to worry me, at
that time, and we got it put right later on - a lot later on, much too late, I
think - was that a number of young patients would queue up with all the other
patients we had in that diabetic clinic. And they had been told that they had diabetes, and that they were
perfectly normal in other respects. But
then they looked along the line of patients waiting to see me, or the clinical
assistant, and they saw patients who‘d had amputations; they saw, occasionally,
a patient who was blind, who had a guide dog; and they... Generally, I mean, some of the patients were
well - most of them were - but some of them were obviously not. And this can‘t have been a good thing. And we began to be conscious of this sort of
thing, and later on, as I say, this was addressed. The other thing was - mindful of what I had
in
Sheffield, where I used to stop for coffee
with my boss in the middle of the clinic - I certainly do like coffee in the
middle of the morning, but I always arranged that my mug of coffee would be on
my desk in front of the patients. And I
hope they would realise that I, in fact, had sips, occasionally, while I was
talking to them, and the clinic did not stop.
|
| | (18) At that time, the idea of having patients...
of having local general practitioners taking responsibility for diabetes had
not yet surfaced. That came, I think, in
the eighties. But by the later
seventies, treatment was becoming available for diabetic retinopathy, and this
was a marvellous step forward. We had
tried, always, to examine the retinae through dilated pupils at annual
intervals, and I suppose we thought we were quite good at it. It was no good doing it through un-dilated
pupils. One had to tell the patients
that they shouldn‘t drive a car for two hours after the dilating drops had been
put in their eyes. I‘m sure they did,
and I‘m sure it didn‘t matter very much. And I‘ve discussed the matter with ophthalmologists, who never ever tell
patients that they shouldn‘t drive when they‘ve had mydriatic drops in, so,
probably, this was an unnecessary precaution. Anyway, so we tried to do that at annual intervals. And if the patient had diabetic retinopathy,
they were referred, actually, to Queen Mary‘s, Sidcup, where laser treatment
was beginning, and also, of course, retinal angiography was started. So that, eventually, became a far better
method of delineating how much retinopathy there was. And so, all this came in in the early
seventies.
When you talked
about the community nurses, did they actually go into people‘s homes?
Yes, our
diabetic community nurse certainly did. And she followed patients into their homes, and helped with their
management of their diabetes, and their anxieties, I‘m sure. They don‘t always tell the doctor what their
anxieties are. In fact, they tell the
doctor, more or less, only what the doctor wants to hear. And if their urine sugars or, later on, blood
sugars were not good, they probably don‘t bother to tell him. But they would tell the diabetic community
nurse, who became an essential linchpin in the whole thing. And I‘m sure there are... we had one, but I‘m
sure there are more, now.
|
| | (19) Now, I‘m now going on to talk briefly about
the British Diabetic Association, and its local branch. It all begins in 1976, when - I think I can
mention him by name - a patient of mine, called Alan Partridge - who is still
very much alive, I saw him only recently - he was diagnosed as diabetic in 1976,
at the age of forty five. He was quite a
senior person in a local cable factory at a place called Erith. And he obviously needed insulin from then
on. I cannot remember whether we
admitted him, or whether the diabetic community nurse took him under her wing. I ought to have asked him a few days ago when
I saw him, but I‘m afraid I didn‘t. Anyway, so his diabetes was fairly well controlled from that moment
on. He was a big fellow: he‘s tall, and
he had... he was quite heavy. And as his
diabetes went on, he began to lose weight, and I got worried that… lest he
might have thyrotoxicosis, and he got worried because I was worried that he
might have thyrotoxicosis. He didn‘t
have, and his weight on the diet stabilised. Anyway, that‘s by the way. So,
one year after diagnosing him, I asked... I mentioned the fact that we did not
have a local branch of the British Diabetic Association, and would he consider
helping us found one. Well, I got the
right man from the word go, and he was absolutely wonderful at setting up this
branch. He came along to the first
meeting. He was elected the chairman. He was the chairman for many years, something
like twenty two years after that. They
collected funds for me; they helped patients; they established a little stall,
which was outside the waiting room for the diabetic clinic, where they sold
things that the BDA offered; they sold other things as fund-raising
manoeuvres. Alan Partridge‘s wife,
Dorothy, did all sorts of things. They
could not have been more helpful in the way they served the diabetic population
in
Dartford, and also
Gravesend.
|
| | (20) And later on, Alan, himself - if he thought
that somebody was in trouble, or wasn‘t understanding their diabetes - would go
along and talk to them and help them. And he had immense knowledge, by this time, of diabetes. And I‘m glad to say that he hardly has any
complication, and I think he claims he‘s never had a hypoglycaemic attack. That might be wrong, but he wouldn‘t have had
many. Anyway, this was good that they
established the fund-raising side of their activities, because glucose meters
came along, around about this time. We
bought some glucose meters, so that patients could measure their blood glucose,
and these were - I think we had about five or six - and these were fairly
expensive. So, a lot of fund-raising
went into their purchase, and I remember myself, with Marjorie Cawley, swimming
at White Oak swimming bath in Swanley. We had to do a sponsored swim, and we had to swim as many lengths as we
could in quarter of an hour. Well, I‘m
not a bad swimmer at breast-stroke, but I don‘t do the crawl, but I did breast-stroke
more quickly than I‘d ever done it before. And I managed sixteen lengths of a - probably - fifty metre bath, I
should think, and came out sweating, which isn‘t usually the case when one
comes out of a swimming pool. Anyway, we
got the money, and Marjorie got... she also swam the same sort of number of
lengths, and we got the money. And we
lent these machines to patients who needed blood sugar measurements, over,
perhaps, a fortnight. And later on, of
course, they became more available, and they were cheaper. At the same time as this, the measurements of
haemoglobin A1c became available; in other words, glycated haemoglobin. This is a... normally present in blood, if
you do electrophoresis to find it, and the glucose molecule gets attached to the
globin part of haemoglobin, and is thereby recognised on electrophoresis. And if blood sugar measurements have been
high over the previous, shall we say, six weeks, then you get a high level of
haemoglobin A1c. So, we were able to
find out what sort of control patients were actually showing. And, of course, we had to get the
equipment. And, once again, Alan
Partridge and the British Diabetic Association came up with money to buy the
machine, which was necessary in order to measure the haemoglobin A1c. And I‘m sure it‘s now regularly done, but it
wasn‘t all that regularly done at that time.
|
| | (21) And how big were your diabetic clinics,
during the 1970s?
Well, I couldn‘t
give you a numerical figure, but I could say they were too big. And what this meant, sometimes, was that
patients weren‘t seen quite as often as they would normally have been. It was three months intervals, and they might
have been extended to six months or so, and that reduced the clinic,
somewhat. I think one got oneself into a
routine - which I quite enjoyed, of course, I enjoyed the job - but one didn‘t
always see the problems presenting themselves until somewhat later, which I
will outline a little bit later, what we did about the size of the clinic. I think one got blinkered a little bit
by... I mean, we thought we were doing
an adequate job, and I suppose, in some senses, we were. But patients were kept waiting in the clinic;
I don‘t suppose more than an hour, but that‘s not really acceptable these
days. And they didn‘t seem to complain
to me - they may well have complained to their GP, and their wives or husbands
- but, as I said before, they don‘t like to upset the doctor!
Why were the
clinics getting bigger and bigger?
Well, I suppose
one got known as somebody who was interested in diabetes. And also, at around about that time, we began
- the hospital itself, not me personally - began to have responsibility for
Gravesend
Hospital. And so, a number of patients would come from
Gravesend, which is about six miles away. So that, and the fact that one got known, I
suppose - and maybe the diagnosis of diabetes was being made clearer by
postgraduate education, and the like - so that‘s why we got more patients
coming in.
|
| | (22) What happened during the 1980s?
Well, around the
early 1980s, with the help of the BDA local branch, and others, we established
a diabetic day centre. This was housed
in an old operating theatre in
West
Hill
Hospital,
in the middle of the town. And the point
about it being in the middle of the town is important, because patients, who
were shopping or working in the town of Dartford, or near, could easily pop
into the diabetic day centre, which was open for most of the working day, five
days a week. And it was staffed with
volunteers from the BDA, and also it became the headquarters of the diabetic
community liaison sister, and other visiting liaison sisters from other areas,
like Sidcup, and so forth. So, this
operating theatre became available, and I had to... there were eight contenders
for the use of this theatre, because space in
West
Hill
Hospital was severely limited. And, anyway, my contentions were okay, and
the hospital secretary said "well, yes, I think you‘d better have
it". So, we had it. And the BDA provided the curtains, and
provided… oh, a television set, I think, and chairs and tables, and probably
the daily paper, and that sort of thing. So, this centre became available for people to come and, we hope, have
their questions answered. And they would
be reassured, if they could be reassured, that they were doing the right sort
of thing. Well, of course, the diabetic
day centre had to be opened. And I was
not responsible for this, but somebody - I know not who - got hold of a fairly
local personality to open it. It was
opened by a man called Gary Mabbutt. I
can mention his name, because I talked to him at the time, and he was well-known,
even then, to have insulin-requiring diabetes. He was, at this time, captain of Tottenham Hotspurs - we‘ll call them
Spurs - football club. And he was
telling me how he - and he went on the radio, as well, I heard him on the radio
- how he used to do a blood sugar at half-time, just to make sure that he
wasn‘t going hypoglycaemic. But he never
did, and his diabetic control was obviously excellent. And when he was interviewed by the BBC lady -
who… why should she know anything about diabetes? Well, she shouldn‘t - but Gary Mabbutt was
able, in a few well-chosen sentences, to tell her exactly what it meant to be a
diabetic, and how one had to live a disciplined life, and so on. It was very impressive. Anyway, he came along with a lot of - and we
had... patients were attending the opening of the day centre, and they were… you know, we said "would you like to
bring your children?", who weren‘t, of course, diabetic, and "would
they like to talk to Gary Mabbutt?", which some of them did. He brought along Spurs‘ football shirts, and
signed autographs, and made a little speech about the diabetic day centre. And I felt that we‘d really got off to a good
start with it, and he was really excellent, and I wrote to him, and thanked him
very much for coming.
|
| | (23) So, at about the same time as the diabetic
day centre - with help from Novo Nordisk, who made insulin from pigs, and now
make human insulin - they had suggested that we establish a diabetic youth
group. And, as I said earlier, we
worried that the young patients were being exposed to what they saw as the
ravages of diabetes. So, we established,
first of all, the youth group. And the
upper age limit, probably, in those days, I think, was about twenty one or two,
or something. We didn‘t actually... I never did paediatric diabetes. That was always done by the paediatrician,
the cut-off point being probably eleven, or something like that. So, from eleven onwards, I would do it, but
before that, it was definitely the province of the paediatrician. Anyway, so we... I remember asking a bright
girl, whose diabetes had developed in 1980, when she was fourteen. I think I can mention her name, because I have
talked to her recently on the telephone: Fiona Hanrahan. She later became a nurse, and is now married
with two very beautiful children. Anyway, so she‘d had diabetes for four years, and she wasn‘t all that
well controlled with her diabetes. And we had… well, the diabetic community
nurse had a few, sort of, light-hearted tussles with her, I suppose. Anyway, she settled down quite nicely, and
was very responsible. And I asked her whether
she would be at all interested in joining what we hoped would be a diabetic
youth group.
|
| | (24) Now, I didn‘t know at the time, and I only
read what she wrote, a few years later, in Balance. She was quite appalled by my letter, asking
that she should become a member of the diabetic youth group. She‘d been told time and again that she had
diabetes, and this was a disorder which could be coped with, and you were just
the same as anybody else, except that you had to abide by certain rules. She‘d had that drummed into her, and here was
I, the diabetic consultant, writing to her, saying could she join something
called a "diabetic youth group". Why was she being singled out? She even thought she might be about the
only person in that part of
England
with diabetes. Had it happened that that
were so, it would be nice. Anyway, she
said, firmly, "no". And then,
on the day in question, she came to the clinic - it was obviously a Thursday,
we were having the opening meeting - and I said "look, Fiona, are you
sure?", because she‘d said "no", but in a very restrained way. Helping the doctor out of his problem, she
said "well, maybe I‘ll come along". So, she did come along. And
another lady was elected to be the chairman, and Fiona was the secretary, and
an excellent secretary she was. And they
had all sorts of activities. They had
monthly meetings in a local surgery, which had a sort of community room. They had all sorts of social events. They asked me to go to them, and some I went
to. They asked me whether I‘d go to the
beachwear disco, which I actually did decline: didn‘t have quite the courage to
go to a beachwear disco; I didn‘t know what I was to wear! Anyway, they had all that sort of thing. We did walks in the countryside, in the
Darent
Valley. And just to show you how little I knew about
diabetes: on the first such walk, which was, I suppose, about ten kilometres,
in rather beautiful country, I packed a haversack with several syringes, some
dextrose solution, a blood glucose monitor. And there were about twenty of us, I think, including my registrar - my
medical registrar came. And, you know, I
had thought "oh well, I‘ll have to worry about people going
hypoglycaemic". Of course, they
were much too wise for that sort of thing. They knew perfectly well what they could do and what they couldn‘t do,
and how far they could walk, and when they would need a little extra food, and
so forth. And I never did that again. I needn‘t have worried at all, but it just
showed how out of touch I was with how people manage their diabetes. The nurses knew perfectly well how to manage
it, of course; it was just me, with this haversack of glucose. And actually, half way round this particular
first walk, Alan Partridge and Dorothy, who I‘ve mentioned before, came with
their camper van, and they provided, oh, I think sausages and burgers, and so
forth, which was probably not the right sort of diet for diabetics to go on all
the time, but these were snapped up, I may say. Anyway, everybody got through the walk without going hypoglycaemic, and
they did many other walks, and I went on several with them, and my wife came on
some occasions. So, anyway, the diabetic
youth group managed, a little later in the eighties, to have their own clinic -
their own part of the clinic - on a Thursday morning, once a month, so that
they were no longer exposed to the results of the complications of diabetes,
and I think that may have helped.
|
| | (25) Why was it that, as you say, that the nurses
knew, perhaps, what it was like to have diabetes, and you didn‘t know what it
was like to have diabetes?
Well, it‘s an
important question, and I have to say that the sheer ignorance of not thinking
the question out properly. Other people,
who looked after diabetes, were probably much better at that than I was. I suppose it might have been engendered by
the way we, as house physicians - well, medical students, house physicians,
registrars - were part of a big apprenticeship system. We did what we saw our elders and betters
doing, and they may not have realised the implications, and so maybe we never,
or I didn‘t get into the way of thinking about the implications of this
disease. My wife, I may say, did. And I‘m most grateful to her for all sorts of
comments. On a totally different subject:
I once encountered a fascinating endocrine cause of high blood pressure, which,
you know, which I was very interested in. On the day, I came home to supper - my wife is totally non-medical - and
I happened to say that I had these suspicions that this condition applied in
this particular case, which meant that the high blood pressure could be
treatable, which it isn‘t usually; not by a curative operation, anyway. So, I mentioned how excited I was about this,
because it gives you intellectual satisfaction to have thought of something,
and then find that your suspicions are, in fact, borne out in fact. So, my wife said "well, how many
children has she?" I said "I
really have no idea". So, this is
just an example of how blinkered I, certainly - and other people may not have
been - but I, certainly, was, in this respect. And later on - it may come out - that the youth group helped me with
this an enormous amount.
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| | (26) I‘m going to talk again, briefly, about the
diabetic youth group, who were, in the main, really very well controlled. I also mentioned that we had this test,
called haemoglobin A1c. And it occurred
to me that if I were to measure - well, they got it measured anyway, when they
came to the clinic - if I were to extract the results of the levels of
haemoglobin A1c in the youth group, and compare it with a roughly similar age group,
in patients who were not... who were attending my clinic, but they were not in
the youth group, and compare the levels of haemoglobin A1c, something
interesting might come out of it. Well,
it did and it didn‘t. It interested me,
because we showed - and I did read this at one of the physicians‘ meetings
around the region - we showed that the levels were, in fact, lower in the
diabetic youth group than in the comparable age group who were not in the youth
group. And, of course, the numbers were
insufficient for it to reach statistical significance. There again, of course, I might mention I was
helped by Burroughs Wellcome. And I just
had to go up to their statistician, who had a thing called a computer - which
there weren‘t many of, in those days - and he was able to work out for me
immediately that it wasn‘t quite significant. But it showed that maybe we were on the right track. And had there been greater numbers, we might
have been able to show that it was of statistical significance. So, going on with the mid-eighties, I
mentioned how busy the clinic had been. Well, by the early eighties, we began to interest local general
practitioners in running their own clinics. Not all of them were interested. They were very busy; they didn‘t want - particularly some of them - to
take on an extra responsibility. But
some of them did, and particularly in
West Kingsdown. I won‘t mention names, but in
West Kingsdown there was a surgery where they were very
interested in doing this.
West Kingsdown is a village out of
Dartford. And the one doctor from the clinic used to
sit in, not every clinic day that I had, because he had his job to do as
well. But gradually, we managed to - I
was going to use the work offload, but I don‘t really like that - we managed to
transfer patients from our clinic, where they were seen, say, once a year, to
the local general practitioner diabetic clinic, where they would manage - with
the aid of the diabetic community nurse, and also their own nurses trained, by
this time, in diabetes - they would manage the control of these patients; both
insulin-requiring and Type 2, non-insulin-requiring diabetes. And this idea took shape. And so, by the time I retired in 1988, we had
a number of surgeries - a number of GPs‘ surgeries - who had an interest in
caring for diabetes, and this meant that one could concentrate more on patients
who had real problems, in the clinic. And it solved, over the years, the problem of enormous clinics. They were described by somebody - I think he
came from Aylesbury - the clinics that we had been used to running, they were
described, by him, as a diabetic dinosaur; ie huge and ponderous, and, dare one
say it, not as effective as they might have been. So, anyway, that was how we solved that one
in the... from the early eighties onwards.
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| | (27) Were there any other developments in the
1980s?
Yes, there
were. We were beginning to manage, from
the early eighties onwards, patients on two or three injections daily, with the
use of the insulin pen, which had come in. This was, as is well-known now, a device for injecting a graduated
amount of insulin. Quite simply, instead
of having to get out a syringe and needle, and so forth, you could just use the
pen to inject, subcutaneously, the insulin. And this helped the control of
diabetes. And at this time, also,
glucose testing strips - glucose Dextrostix, and others - were available,
which, of course, initially had to be bought. And that‘s where the local diabetic group came in, by helping to fund the
purchase of these glucose testing strips. Then, in the mid-eighties, I think, these - after an argument with the Department
of Health from the British Diabetic Association - they began to be… they were
prescribable. And so, patients could
then have these strips prescribed, and they could do their own blood sugar
measurements, and help with their own control. I‘m going to mention, now, diabetes in pregnancy. I mentioned, earlier, that when I was in
Sheffield as a senior registrar, I was interested in the
end results, and the management of diabetes in pregnancy, and this went on
throughout my career. And one realised
that what we ought to have was a combined clinic. In King‘s
College
Hospital,
they had said, initially, there should be a weekly clinic, attended by the
diabetic specialist and also by the obstetrician, who was vital to help decide
what form of labour, or Caesarean... when Caesarean sections should be done,
and so on. Unfortunately, all three
obstetricians were very busy people - and I can recognise that - and there
literally was no time - we still did our clinic on Thursday mornings only - there
was no time when one could actually have a combined clinic, where we would both
see the patient at the same time. We did
fairly well, I think, by interesting one - Alan Chester, who was one of the
obstetricians - who was interested in this. And so, we used to talk over lunch, and that sort of thing, about
individual patients. So, although we
didn‘t have an actual clinic, the nurses involved in the obstetric department
got interested in it too. And I think
they read a paper to their organisation about the management of our diabetic
pregnancies, because we worried a lot about still births, because they used to
come out of the blue, at say thirty six or thirty seven weeks, when you thought
you‘d got good control, and bang, there would be a still birth. And this, of course, is… I think rates were originally around 30%, or
something awful. And I believe, now, it
is now down to something like 7%. Still
pretty awful - well, awful for the woman concerned, and the husband - but much,
much better. So, our obstetric nurses
read this paper, involving, I think, haemoglobin A1c and general control, and
when labour should be terminated, because that was thirty six weeks. And as diabetic control improved, it went up
to about thirty seven and a half weeks. And
I don‘t know what it is now, but I guess it‘s still a little bit earlier than
full term.
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| | (28) And any more memories from the 1980s?
Yes, I suppose,
in the 1980s, we began to be more interested in the treatment of hypertension,
in people with diabetes. This has
advanced, of course, an awful lot from the 1980s, and is now much more
understood, and much more… and many more interesting drugs are available than
were then. But we realised that in order
to reduce the incidence of renal failure, which was all too common, that we had
to concentrate on the management of high blood pressure in pregnancy, and our
levels of acceptable blood pressures were much lower than they had formerly
been. So, this was another aspect of
treatment, in the 1980s, which we hope - and I‘m sure it did - manage to reduce
the incidence of renal failure, or the time at which it came on.
Did your
approach to diet change, at all, in the 1980s?
I‘m sure our
approach to diet did change in the 1980s. We had, by this time, a marvellous new dietitian - she‘d been there a
number of years. And she began to
introduce the idea of a high-fibre diet - which, I may say, she introduced to
myself and my wife at the same time, without realising it - but high-fibre diet. And the reduced insistence on ten gram carbohydrate
portions was all coming in at the time. I very much left the dietary management of all these patients with
diabetes to her, and I think she‘s still there at the hospital. And I can‘t be more specific than that,
except that it was a great relief for everybody that they didn‘t have to weigh
ten gram portions of this, that and the other, which had been necessary. I suspect she started before the 1980s; in the
latter seventies, actually. But she was
joined by another dietitian, so that there were two, which we‘d never had
before. And we realised - or the
authorities realised - how important it was to get proper dietary advice. So, these two, I think, to an extent, revolutionised
the management of diabetes, from late seventies, right through the eighties.
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| | (29) So, now we come to your retirement, in
1988. What are your memories of that?
Well, my
memories are that I was due to give a talk - I think it was the day before I
actually retired - to Queen Mary‘s Hospital, which is not far from where I live. And I gave an outline of my experience in
diabetes, throughout, you know, well, twenty five years in Dartford, and, of
course, a bit before that as registrar, and so on. And one of the points I made, in the course
of this talk, was that we ought not to talk about diabetics. We ought to talk about people with diabetes,
in the same way as I had got used to talking about… not epileptics - that‘s got
nothing to do with diabetes, of course - not talk about epileptics, but talk
about people with epilepsy. So, in the
same context, we should talk about people with diabetes. I think this, at the time… in a very good-natured
way, some people said "well, why bother? We talked about them as diabetics; we always have been". I have a feeling that perhaps this has gained
ground, a bit, and we tend to talk about people with diabetes a little bit more,
and I think that‘s probably helpful. Anyway,
so I outlined my experience with diabetes, which I have now talked about. But I ended up by saying that there were some
patients, who I had - and I‘m really talking now about insulin-requiring Type 1
diabetes - some patients, who, despite apparent pretty appalling diabetic
control, did not suffer any complications. There were, of course, others who, despite long-standing good control,
still exhibited these complications. And
I don‘t think - I don‘t follow the literature like I once did - but I don‘t think
the first group - that is those who had appalling diabetic control, and no
complications over a period of years - I don‘t think, even now, the explanation
for the first group has been totally elucidated. It may have something to do with genetics, I don‘t
know, but maybe somebody does know, and it will be interesting to know whether
this comes out. But, of course, I may
say that diabetic control now, in the years since I retired, has been
enormously transformed. There have been
targets, which have been established internationally, for the good control of
diabetes, which we never had before. And
this means that patients, themselves, know what sort of control and what sort
of treatment they should have. And
there‘s no doubt at all that this has resulted in a better life for these
patients. And, I mean, there is, round
the corner, islet cell transplantations, which, in fact, may not be round the
corner; it is, in fact, happening now, so that a number of patients have no
longer to have either any injections, or quite so many. There‘s continuous insulin infusion, which a
lady in the locality, who runs the diabetic group in and around Sidcup, who has
it herself, and that‘s revolutionised her life. And so, there‘s no doubt whatever, that advances are being made at great
speed, and maybe that this disease may eventually not be nearly as common as it
is now.
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| | (30) One other memory I have, round about that day
that I retired in September 1988, was when the members of the diabetic youth
group, with the chairman and Fiona Hanrahan as secretary, invited my wife and I
to supper in a pub in Erith. I can‘t
remember exactly what we ate - it was a good meal. But what I realised was that just before the
main course, they would get out their insulin pens or their insulin syringes,
and they would give themselves an injection, sometimes actually through their
trousers, which I‘ve never advised, but I‘m sure it doesn‘t matter. And there were sort of insulin syringes
rolling about the table. And nobody
thought anything of it, because that‘s how they lived, you see. And I realised, then, how little I really
knew, even then, about what it was like to be an insulin-requiring diabetic, or
even Type 2 diabetes, for that matter. And so, I realised that they had taught me, throughout the years that we
did these various social events, and so on - and country walks, and all that
sort of thing - how much I learnt from them about diabetes, and how valuable
that was. They also, as a leaving
present, gave me a miniature rose - which is in the garden, twenty five yards
from where I am now - called Darling Flame. It‘s a miniature rose, which is now in flower, and I‘ve kept it
going. It tends to be swamped a bit by
other roses around. And I talked to
Fiona Hanrahan, when I sent her her Christmas card, about Darling Flame, and
I‘m sure she can‘t be bothered at all about what‘s happened to Darling Flame,
but it‘s still going very well. So, my
message, which I gave to the group at the hospital up here, was how much I had
learned from looking after diabetes. And
my message, really, to them - and to anybody else, for that matter - was: learn
from your patients, as well as treating them.
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